7 Indian Genetic Sequencing Startups You Can’t Ignore

With the age of personalized medicine at the brink, it only makes sense that Indian genetic sequencing startups mushrooms to chip in on this medical revolution. With that spirit in mind, here’s a list of 7 startups which provide genetic sequencing as a service.
1. Ganit Labs Bio-IT center– An independent not-for-profit research Centre established as a public-private partnership initiative between the Institute of Bioinformatics and Applied Biotechnology and Strand Life Sciences, both in Bangalore, India.
2. Medgenome– MedGenome Inc. is a genomics-based diagnostics and research company delivering the best of health care by decoding the genetic information contained in an individual’s genome. They are the first mover and market leader in genomics-based diagnostics and research from India with global offices in San Francisco and Boston and is considered to be among the pioneers of Indian genetic sequencing startups.
3. Mapmygenome– Mapmygenome is a molecular diagnostics company to make people proactive about their health. They offer personalized health solutions based on genetic tests that help people to get to know about themselves. By combining genetic health profile and health history with genetic counseling, Mapmygenome provides actionable steps for individuals and their physicians towards a healthier life. Mapmygenome is focused on preventive health care through healthy habits.
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4. Xcelris– Considered to be among the most versatile of Indian genetic sequencing startups, They cutting-edge solutions to researchers across fields such as agriculture, human health, animal science, wildlife conservation, bio-energy, microbial and environmental genetics. Xcelris partners with the biotechnology industry, academia, research institutes and individual researchers in India and abroad. They cater to the needs of researchers by their comprehensive service portfolio ranging from Molecular biology kits, Oligosynthesis services, Sanger Sequencing services, Next Generation Sequencing and Bioinformatics analysis.
5. SciGenom– A Genomics R & D Services company, that provides genomic sequencing and bioinformatics services to life sciences and healthcare businesses globally as well as academic and government institutions in India. SciGenom started operations in Jan 2010. It is headquartered in Cochin, India with offices in Chennai & Hyderabad in India and San Francisco in the U.S. SciGenom is an NABL and ISO certified company, with a fully functional state-of-the-art molecular biology laboratory in Cochin and over 100 employees. It also has an R& D lab that is recognized by Department of Scientific & Industrial Research (DSIR), Ministry of Science & Technology, Government of India.
6. Jai Health– They develop and commercialize preventive health, genomic, molecular diagnostic and personalized medicine solutions for India, Asia, the Middle East and Africa. Research and innovation are at the heart of what they do and they build each solution up from the ground tailored specifically for the markets we serve.
7. Xcode Life sciences– With a panel that covers over 300 parameters that screen for several aspects of disease predisposition, skin aging manifestations, nutrition, and fitness, based on personal genomics. The custom-made genomic testing panels have been hand-picked by their researchers using stringent selection criteria, Xcode’s core area of focus is genomics. Their products are offered in India, Australia & South Africa.

With these string of startups offering the basic requirement of genome mapping it’s only a matter of time before the field of personalized medicines booms in the medical sector. Watch out for these companies and brace yourself for the unparalleled efficiency of personalized medicine!

Personalized Medicine In India

Personalized medicine in India is a young but rapidly advancing field of healthcare that is informed by each person’s unique clinical, genetic, genomic, and environmental information. It is about making the treatment as individualized as the disease. It involves identifying genetic, genomic, and clinical information that allows accurate predictions to be made about a person’s susceptibility of developing the disease, the course of the disease, and its response to treatment.

Specific advantages that personalized medicine may offer patients and clinicians include:

 Ability to make more informed medical decisions

 Higher probability of desired outcomes thanks to better-targeted therapies

 Reduced probability of negative side effects

 Focus on prevention and prediction of disease rather than reaction to it

 Earlier disease intervention than has been possible in the past

 Reduced healthcare costs

Advances in Genomics Technology Have Set the Stage for a Revolution in Personal Genomics that will ultimately work towards preventive healthcare, disease burden reduction and Personalized Medicine in India. Positive hqdefaultBioscience has partnered with Medanta – The Medicity to launch India’s first personal genomics clinic, which offers state-of-the-art facilities and services in preventive healthcare and personalized medicine within the country. This partnership seeks to offer comprehensive personal genomics services to the customers along with advice from leading experts associated with the Medanta – The Medicity under one roof.

Advances in genomics now enable scientists to examine the DNA of each-and-every individual and then predict if the person would be susceptible to a particular disease or whether a particular medicine is suitable for that person in case he falls sick. This is where pharmacogenomics comes into play. Companies have started investing in pharmacogenomics as it offers several advantages such as the elimination of the unpredictable nature of drug development, bring new products to the market and the company could also benefit up to $200-to-$500 million for each drug.

main-thumb-t-265506-200-aduztyxvjxylkhxrkxzmaztfmjqdxhyxA start-up company called Xcode Lifesciences has come up with the InDNA technology to provide solutions to lifestyle-related diseases such as coronary, diabetes and obesity. A person has to order the test online after which a saliva kit will be shipped to the customer. This saliva kit is completely non-invasive and safe. DNA extracted from the saliva will then be used to determine the allelic information of the individual using high-throughput genotyping techniques.

sgdsdgssfgsdfgdNutraGene launched the country’s first commercial genetic test for type 2 diabetes. NutraGene’s Type 2 Diabetes Genetic Scan is a DNA testing service that screens DNA variations that have been widely replicated as risk factors for type 2 diabetes. It is based on a buccal (cheek) swab sample and the methodology of targeted mutation screening (genotyping).

AvesthagenAvesthagen is another major player focusing on pharmacogenomics field. One of the major projects of the company is the AVESTAGENOME Project. It is a system biology-based study of the Parsi population to determine the genetic basis of longevity and age-related disorders. This study aims to develop a model for pharmacogenomics-based therapies, development of biomarkers for predictive diagnostics and drug discovery and to enable the archiving of the genome of the community. Avesthagen started this Rs125 crore project in 2007.

Despite the optimism expressed regarding the impact that this field might have on the health of people, many barriers need to be crossed. Researchers, diagnostic firms and regulatory authorities need to establish methodologies by which to judge their effectiveness. Application of genomic and personalized medicine in India needs a change in the regulatory system.